🌿 Conditions · Sleep

Cannabinoids and sleep

Sleep is one of the few areas in this library with guideline-level sources alongside mechanistic work, which makes the boundaries unusually explicit.

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Reading this collection

This cluster carries a wider range of evidence tiers than most — from a national-academies summary through systematic review to mechanistic work on sleep architecture. Read the tier label before the finding.

Sleep endpoints are also notoriously sensitive to how they were measured: self-reported sleep quality and polysomnographic architecture are different outcomes and do not substitute for one another.

The evidence in this library

7 source-linked studies — 4 scientific source · 2 guideline / official boundary · 1 peer-reviewed review. Each links to its source; identifiers are shown where the record carries them.

  1. Cannabidiol and Sleep Disorders — GABA-A Potentiation, REM Architecture

    2018 · PubMed · CBD

    Scientific source

    PMID 29381457

  2. Summary — The Health Effects of Cannabis and Cannabinoids

    2017 · NCBI Bookshelf · Cannabinoids, nabiximols

    Guideline / official boundary

  3. Cannabinoids and Sleep: Systematic Review of Current Evidence

    PubMed · CBD, THC, CBN

    Guideline / official boundary

    PMID 25271780

  4. CBD and Cannabinoids for Sleep Disorders: Large Clinical Case Series

    PubMed · CBD, CBN

    Scientific source

    PMID 32350861

  5. Linalool (Lavender / Sleep Sutra): GABA-A Anxiolytic and Sleep Onset Terpene

    PubMed · Linalool

    Scientific source

    PMID 12587690

  6. Nardostachys jatamansi: Phytochemistry, Ethnomedicine and Pharmacology

    PubMed · Jatamansi

    Peer-reviewed review

    PMID 38042505

  7. HPA-axis modulation with botanical interventions (Ashwagandha)

    NCBI

    Scientific source

    PMID 33650944

How to read this evidence

These are the boundaries recorded against the studies above, reproduced as written in the library: